新闻分类
--没有找到相关新闻--
联系方式
- 北京杰辉博高生物技术有限公司
- 联系人：杨经理
- 电话：4000610918
- 邮箱：1261299569@qq.com
- 地址：北京市海淀区乾通天商务楼
Anti-HLA-C Polyclonal Antibody
发布时间： 2023-02-14
产品简介
| 单位 | 支 |
| 靶标 | HLA-C |
| 别名 | HLA-C;D6S204;HLA-JY3;HLAC;HLC-C;MHC;PSORS1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:100-300. |
| Gene ID | 3107 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P10321 |
| 蛋白分子量 | 37/41kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm |
| 免疫原 | A synthetic peptide of human HLA-C |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described |
| Public Immunogen Range | 40-90/366aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Predicted:Dog Chimpanzee Monkey |
| 应用 | WB IHC |
| 规格 | 50ul 100ul |
