• 商品编号：254316

• 品牌：Abbiotec

• 公司：Abbiotec, LLC.

• 公司分类：antibodies

• Size：0.1 mg

• Cat. No.：254316

• Unit：0.1 mg

• Isotype：Rabbit Ig

• Applications：E

• Species Reactivity：H

• Format：Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.

• A：

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.