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peprotech 300-65重组人β-防御素4价格,现货供应peprotech因子原装说明书
  • 发布日期: 2014-12-25
  • 更新日期: 2023-04-25
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英文名称 Recombinant Human BD-4
纯度 %
别名 仅供科研使用
规格 100µg

peprotech 300-65重组人β-防御素4价格,现货供应peprotech因子原装说明书

300-65
Synonyms:
Beta-Defensin 104, DEFB4
Description:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system.  The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds.  To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6.  β-defensins are expressed on some leukocytes and at epithelial surfaces.  In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells.  The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence.  β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.   BD-4 is expressed in the testes, stomach, uterus, neutrophils, thyroid, lungs and kidneys.  In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes.  Recombinant Human BD-4 is a 6.0 kDa protein containing 50 amino acid residues.

peprotech 300-65重组人β-防御素4价格,现货供应peprotech因子原装说明书
 
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peprotech 300-65重组人β-防御素4价格,现货供应peprotech因子原装说明书