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Recombinant Rat VEGFA/VEGF164
  • 品牌：国产
  • 价格： ￥10/瓶
  • 发布日期： 2020-10-20
  • 更新日期： 2023-04-25
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品牌 国产
货号 P00193
用途范围 科研实验
英文名称 Recombinant Rat VEGFA/VEGF164
纯度 %
保质期 一年
是否进口 否
Known asVascular endothelial growth factor A;Vascular permeability factor;VEGF;VEGF-A;VPF
Derived fromP. pastoris
PurityGreater than 95% as determined by reducing SDS-PAGE.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
ShippingThe product is shipped at ambient temperature.
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
EndotoxinLess than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
BackgroundVascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic , paraventricular nuclei and the choroid plexus of the pituitary, and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide, and alternative splicing of rat VEGF gene produces isoforms of 120, 144, 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and play important roles in inducing endothelial cell proliferation, promoting cell migration, inhibiting apoptosis and inducing permeabilization of blood vessels.

Recombinant Rat Vascular Endothelial Growth Factor A is produced by our Yeast expression system and the target gene encoding Ala27-Arg190 is expressed.

注意：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。


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