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- 北京杰辉博高生物技术有限公司
- 联系人:杨经理
- 电话:4000610918
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- 地址:北京市海淀区乾通天商务楼
Cellartis® hiPS Beta Cells (from ChiPSC22) Kit
- 品牌:国产
- 货号:026541
- 价格: ¥10/盒
- 发布日期: 2021-02-02
- 更新日期: 2023-04-25
产品详请
品牌 | 国产 |
货号 | 026541 |
用途范围 | 科研实验 |
英文名称 | Beta Tubulin Polyclonal Antibody |
纯度 | % |
保质期 | 一年 |
是否进口 | 否 |
Cellartis®β细胞是由我们的人iPS细胞系(ChiPSC12;ChiPSC22)分化而来,制备成单细胞悬液,冻存在管中。该试剂盒含有β细胞,包被涂层,基础培养基,以及补充剂。目前提供两种试剂盒供选择,每个试剂盒中的β细胞都来自健康人供体,其中Cellartis hiPS Beta Cells (from ChiPSC22) Kit(Code No. Y10106)的供体细胞是对糖尿病易感的HLA(human leukocyte antigen人类白细胞抗原)类型,HLA-A*02:01。 ■ 产品特点· Beta cells from ChiPSC12 and ChiPSC22 originate from healthy human donors· Beta cells from ChiPSC22 originate from a donor with a diabetes-susceptible HLA type, HLA-A*02:01 (Marron et al. 2002)· Beta cells from ChiPSC22 can be used alone or in combination with beta cells from ChiPSC12, which have an alternate HLA type· Cells show protein expression of insulin/C-peptide, MAFA, NKX6-1, PDX1, and UCN3· Cells demonstrate insulin and C-peptide secretion· Cells were derived with a protocol that mimics embryonic development· Cells provide reproducible and biologically relevant data ■ 更多信息Donor informationThe tissues used for the reprogramming of somatic cells into hiPSCs are from donors who have signed informed consent which outlines in detail the purpose of the donation and the procedure for processing of the donated tissue. In order to protect the privacy and the confidentiality of the donors, all identifiers associated with the donors have been removed. The donor consent was obtained for commercial use. The donation did not result in any financial gain for the donors.· ChiPSC12 was sourced from skin fibroblasts from a healthy 24-year-old European/North African male volunteer (77 kg/177 cm).· ChiPSC22 was sourced from skin fibroblasts from a healthy 32-year-old European/North African male volunteer (74 kg/179 cm) with a diabetes-susceptible HLA type, HLA-A*02:01. HLA typification data for each line is shown below. ■ 产品应用· Disease modeling for diabetes· Compound screening for insulin secretion and regulation· Beta-cell functionality· GSIS (glucose-stimulated insulin secretion) analysis· Incretin response studies· Autoimmune beta-cell destruction· Pancreatitis and beta-cell function· Transdifferentiation | |
■ 产品组成 | |
· 1 vial (4.8 x 106 viable cells) of Cellartis hiPS Beta Cells (from ChiPSC12) or ChiPSC22 · 11 vials (360 μl/vial) of Cellartis Beta Cell Supplement · 1 tube (4 ml) of Cellartis Beta Cell Coating · 1 bottle (160 ml) of Cellartis Beta Cell Basal Medium · 1 bottle (30 ml) of Cellartis Beta Cell Basal Medium 2 |