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- 北京杰辉博高生物技术有限公司
- 联系人:杨经理
- 电话:4000610918
- 邮箱:1261299569@qq.com
- 地址:北京市海淀区乾通天商务楼
- 品牌:Peprotech
- 产地:USA
- 型号:支
- 发布日期: 2014-03-25
- 更新日期: 2023-04-25
Recombinant Human NGF-β 450-01 Peprotech细胞因子报价
Catalog Number:
450-01
Synonyms:
NGF-β
Description:
β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.
AA Sequence:
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED 50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10 6 units/mg.
Recombinant Human NGF-β 450-01 Peprotech细胞因子报价
Cross Reactivity:
Chicken, Hamster, Mouse, Rat, Human, Leech
Research Interests:
Angiogenesis/ Cardiovascular | Chemotaxis | ||
Diabetes / Weight Regulation | Inflammation | ||
Neurobiology | Stem Cells & Differentiation | ||
Wound Healing |
Country of Origin:
USA
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