AF-300-01A Recombinant Human TNF-a peprotech细胞因子说明书

Recombinant Human TNF-α
Catalog Number:
AF-300-01A
Synonyms:
Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin
Description:
TNF-α is a pleiotrophic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant human TNF-α is a soluble 157 amino acid protein (17.4 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein. Manufactured using all non-animal reagents.
AA Sequence:
VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINRPD YLDFAESGQV YFGIIAL
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50as determined by the cytolysis of murine L929 cells in the presence of Actinomyocin D is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Cross Reactivity:
Cow, Mon key, Mouse, Rat, Sheep, Human, Dog, Pig, N/A, Human + Virus

北京杰辉博高生物技术有限公司经营各种一线品牌产品： Sigma ， Amresco （大量现货）， QIAGEN 、 Elisa 试剂盒， Abcam 、 CST ， Hyclone 、 Gibco 、 PAA 胎牛血清，实验耗材 -Corning 、 Axygen 大龙移液器、艾本德移液器等知名品牌。货品齐全价格优惠。全国销售热线： 010-57269778 。